LDI is the only non-invasive, contactless & FDA approved method to visualize microcirculatory perfusion. PUBMED lists more than 380 publications that refer to LDI. Aïmago builds on this heritage: We have made LDI real-time and a valuable tool for day-to-day clinical work.

Skin is illuminated by a low power infrared Laser. Part of the light penetrates the skin where it is reflected by the red blood cells in the capillaries. As these blood cells are moving, the reflected light is subject to the Doppler shift, which is a small change in frequency.

We have replaced the traditional Laser scanning method with a full-field imaging approach that delivers 12 images / second and removes patient movement, breathing and heart beat artifacts. [3,4]

LDI measures perfusion, which is the product of concentration multiplied by the average speed of the red blood cells in small vessels. [1,2]

The units are arbitrary and absolute LDI values only have a limited meaning. The way to use LDI is to make intra-individual relative measurements. In other words, LDI perfusion levels should be compared between body parts on one patient, or by following one skin area over time.

1. Bonner, R. et al. Model for laser Doppler measure-ments of blood flow in tissue. Analysis 20, (1981).

2. Briers, J.D. Laser Doppler, speckle and related techniques for blood perfusion mapping & imaging. Physiological Measurement 22, R35-66 (2001).

3. Serov, A et al. Laser Doppler perfusion imaging with a complementary metal oxide semiconductor image sensor. Optics Letters 27, 300-2 (2002).

4. Leutenegger, M. et al. Real-time full field Laser Doppler Imaging. Optics Express 2, 2041-2047 (2011).